2017 CRWAD Dedicatee: Katherine M. Kocan, PhD
Katherine M. Kocan, PhD
Regents Professor, Veterinary Pathobiology
Oklahoma State University
Katherine Kocan, Ph.D. and OSU Regents Professor Emerita, recently retired from a 42 year career at the Center of Veterinary Health Science, Oklahoma State University where her research was focused on ticks and tick-borne diseases. Throughout her career, Kocan and her team and graduate students published over 325 scientific papers which included defining the role of ticks in transmission of the cattle diseases, anaplasmosis and heartwater, development of vaccines against ticks, definition of molecular interactions between ticks and pathogens, and the development of a sheep model for studying tick transmission of the pathogen that causes human granulocytic anaplasmosis. She earned a B.A. degree (1968) from Hiram College in Hiram, Ohio, an M.S.P.H. (1971) from the University of North Carolina at Chapel Hill and her Ph.D. (1979) from Oklahoma State University. She held the Walter R. Sitlington Endowed Chair in Food Animal Research from 1996-2016.
Kocan was honored with the Distinguished Alumni Award and the J.J. Turner Alumni Achievement Awards from Hiram College (1984, 2010). She was named Fellow of the Society for Tropical Veterinary Medicine (STVM) in 2007 and was the Dedicatee of the 9th Biennial meeting of STVM. She was an invited speaker at the Italian Society of Veterinary Sciences Special Symposium in Palermo, Sicily (2006) and the Conference of Research Workers on Animal Diseases (CRWAD) (2010). She served as President of several organizations including STVM (1993), the OSU Chapter of Sigma Xi (1997), CRWAD (2003), and the OSU Regents Professors (2006). She served on the Oklahoma Center of the Advancement of Science and Technology, Health Research Committee for 20 years and was the Committee Chair from 1998 to 2004. Kathy served as a faculty mentor to many students and faculty, including Native Americans in Biological Sciences, Women in Science and the NSF Advance OSU Program. She received the Innovator of the Year “On the Brink” Award from the Journal Record in 2001 and the OSU Regents Distinguished Research Award in 2003. In 2006, Kocan received two Patent Recognition Awards. She was honored with the CVM Beecham Award for Research Excellence in 1986 and the Pfizer Research Award in 1996 and 2010.
2017 Distinguished Veterinary Immunologist: Ray Waters, DVM, PhD
2017 AAVI Immunologist of the Year
Ray Waters, DVM, PhD
“Immunology of Bovine Tuberculosis: Perspectives on one health approaches and defining correlates of protection versus infection”
Veterinary Medical Officer, National Animal Disease Center, Tuberculosis Research Project
Dr. Waters received a BS in Biological Sciences and DVM from Auburn University in 1985 and 1988, respectively, and a PhD in Immunobiology (w/ Dr. Jim Harp) from Iowa State University (ISU) in 1996. After completing a post-doctoral appointment with Dr. Mike Wannemuehler at ISU from 1997-2000, he joined the Bovine Tuberculosis Research Project at the National Animal Disease Center (NADC) in Ames Iowa as a Veterinary Medical Officer. He has contributed to over 175 peer-reviewed publications, 23 review articles/book chapters, 264 meeting abstracts/presentations and served as editor for Clinical and Vaccine Immunology from 2007-2014. A predominant emphasis of Dr. Waters’ career has been the characterization of adaptive immune responses to infectious agents by cattle and other hosts of veterinary interest. This work has required development of experimental models of infection and in many instances use of BL-3Ag biocontainment facilities. The primary focus of Dr. Waters’ research at NADC over the past 17 years has been the evaluation of humoral and cellular immune responses by cattle to Mycobacterium bovis infection, discovery and development of vaccines for the control of tuberculosis (TB) in cattle and white-tailed deer, and development of improved ante-mortem diagnostic assays for the detection of TB-infected animals, of which, has resulted in serum-based tests approved for use in cattle, deer, and elephants. Additionally, Dr. Waters provides scientific support on the development, implementation, and troubleshooting of TB diagnostic tests for the National Veterinary Services Laboratories and APHIS TB program staff.
For over 100 years, the study of Bovine TB has been a classic model of the One Health Approach to infectious disease research as evidenced by the development in cattle prior to use in humans of essential diagnostic tests (e.g., tuberculin skin test and interferon-g release assays) and the primary vaccine (i.e., BCG) used in human TB. As such, Dr. Waters’ research to determine immune correlates of protection to bovine TB, novel host biomarkers of infection, and approaches to differentiate infected from vaccinated animals (DIVA) are also been of relevance to human TB. Recent studies in his laboratory on the characterization of Th17 immune responses, central and effector memory subsets, and polyfunctional CD4 T cell responses as related to disease severity (i.e., gross/microscopic lesions and mycobacterial colonization) and vaccine efficacy have laid the groundwork for development of vaccines designed to target protective phenotypes in the immune response to bovine TB. In collaboration with Dr. Konstantin Lyashchenko at Chembio Diagnostics Inc., Dr. Waters’ research on antibody responses to M. bovis infection in cattle have defined antigen recognition profiles, qualitative and quantitative boosting effects of PPD administration for skin test on serum antibody responses, and detection of immune complexes with associated mycobacterial antigens in sera and other body fluids of infected cattle. These studies on both cellular and humoral immune responses have led to practical applications for improved diagnostic approaches as well as to a better understanding of the immunopathogenesis of bovine TB.
Dr. Michael Dryden is the 2017 American College of Veterinary Microbiology Distinguished Microbiologist. He received his Bachelor of Science Degree in 1982 and his Doctor of Veterinary Medicine Degree in 1984 from Kansas State University. At Purdue University he earned both a Masters Degree (May 1988) and a PhD (May 1990) in Veterinary Parasitology. It was while a graduate student at Purdue that the veterinary students started calling him “Dr. Flea”. He has been on the faculty of Kansas State since 1990 where he is a Full Professor in the Department Diagnostic Medicine/Pathobiology.
His research has changed the veterinary profession’s understanding of flea and tick ecology. In addition, his research team has developed novel methods for evaluating flea and tick control products and proposed new concepts that revolutionized flea and tick control. Between 1988 and 2017 these various research efforts have resulted in over 140 published journal articles and 13 book chapters, a pictorial atlas of veterinary parasitology and being invited to lecture in over 20 countries. Dr. Dryden has served on numerous national, international, and university committees. Including serving as a board member on the International Ectoparasite Symposium, the National Conference on Urban Entomology and was a founding member of the Companion Animal Parasite Council.
2017 Schwabe Symposium Honored Speaker: Ian Gardner, BVSC, MPVM, PhD
2017 AVEPM Schwabe Symposium Honored Speaker
Ian Gardner, BVSC, MPVM, PhD
“Design, analysis and reporting of test accuracy studies in animals: progress, challenges and opportunities”
Epidemiology and Canada Excellence Research Chair
Atlantic Veterinary College, University of Prince Edward Island
Ian Gardner, BVSc, MPVM, PhD is a Professor of Epidemiology and Canada Excellence Research Chair at the Atlantic Veterinary College, University of Prince Edward Island. Dr. Gardner has held faculty positions at the University of California, Davis and prior to arriving to the U.S. he was a Veterinary Officer with the Department of Agriculture in New South Wales, Australia. Dr. Gardner served as the president of both the Association for Veterinary Epidemiology and Preventive Medicine (AVEPM) and the Conference of Research Workers in Animal Diseases (CRWAD). He also served as an associate editor of Preventive Veterinary Medicine and on the editorial board of 6 other journals.
Dr. Gardner and his collaborators are world leaders in diagnostic test evaluation/validation in the veterinary sciences. An important focus of Dr. Gardner’s work has been the fields of evaluation of diagnostic test in the absence of a perfect reference test, developing quality standards for diagnostic tests, and pooled testing for detection of diseases in animals. His work with collaborators has led to a widespread acceptance of the legitimacy of the approach for test evaluation for chronic infectious diseases of animals. Additionally, his work has influenced policies of the World Organization for Animal Health (OIE) and methods he developed with collaborators are now incorporated in the 2016 OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Dr. Gardner played a leading role adapting the Standards for Reporting of Diagnostic Accuracy (STARD) statement, which was published in 2003 to increase relevance to terrestrial and aquatic animals. Finally, Dr. Gardner has made major contributions to the use of pooled diagnostic testing as a cost-effective approach to the detection of diseases of low prevalence, to the classification of populations as infected or not, and to the estimation of within-population prevalence.